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IGF1-LR3 (Insulin-like Growth Factor-1 Long R3) is a modified version of the hormone known as Insulin-like Growth Factor (IGF or IGF-1). IGF-1 is a hormone naturally found in your blood, which manages the effects of growth hormone (GH) in your body.
The “insulin” portion of the name refers to the fact that IGF-1 has insulin-like actions in some tissues. It does decrease blood sugar levels, but not nearly to the extent that insulin does. Its fundamental mechanism is to stimulate growth, such as in epidermal, platelet-derived, and nerve growth factors. IGF’s differ from other growth factors in that they are the only ones with well-described endocrine actions in human. The endocrine system produces and releases hormones and regulates many body functions, including metabolism, growth, mood, and reproduction.
Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid endogenous neuropeptide hormone found throughout the central nervous system, peripheral nerves, immune system, lungs, and gastrointestinal tract. It is a potent regulatory peptide widely distributed in the brain, lungs, immune cells, gut, cardiovascular system. It exerts its effects through cAMP signaling, vasodilation, immune modulation, neuroprotection, and anti-inflammatory cytokine balance. Key cellular actions include suppression of TNF-a, IL-6m IL-12, increases IL-10 (anti-inflammatory cytokine), regulates Th1/Th2/Th17 balance, and protects endothelial and epithelial barriers.
Kisspeptin is a neuropeptide produced by the hypothalamus, a part of the brain that controls the release of several important hormones in the body including gonadotropin-releasing hormone (GnRh), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Kisspeptin plays a major role in reproductive function in both men and women, secretion of aldosterone (which regulates water and salt balance), tumor suppression, and kidney function. Kisspeptin was originally named Metastin, a direct reflection of its ability to prevent the spread of cancer.
PT-141 is a synthetic peptide for treating sexual dysfunction and other related issues. It is intended to enhance sexual desire and increase sexual satisfaction in both men and women. It works by stimulating the melanocortin system, which is responsible for regulating sexual arousal, among other functions. Not only is there a remarkable enhancement of libido, but increased orgasmic responses as well.
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